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Hassan
1.Which of the following particles is used in the gene gun method?
A. Iron particles
B. Aluminum particles
C. Silver particles
D. Iron particles
2.Which of the following shows the location of the inserted genes?
A. Palindromic sequences
B. Resistance gene
C. Restriction site
D. Palindromic sequences
3.Which of the following is NOT true for agrobacterium?
A. Horizontal gene transfer
B. Gram positive bacteria
C. Causes tumor in plants
D. Horizontal gene transfer
4.9. Name the phylum which is characterized by the presence of notochord.
A. a) Chordata
B. b) Hemichordata
C. c) Echinodermata
D. a) Chordata
5.Name the disease caused by Agrobacterium in plants?
A. Crown gall disease
B. Black knot
C. Downy Mildew
D. Crown gall disease
6.10. Name the first vertebrate which possessed amniotic egg?
A. a) Amphibia
B. b) Aves
C. c) Reptilia
D. a) Amphibia
7.11. Which of the following is known as scavengers in the marine ecosystem?
A. a) Lamprey
B. b) Hagfish
C. c) Scoliodon
D. a) Lamprey
8.The map of the chromosome which shows identifiable sites is called?
A. Gene expression
B. Genome sequencing
C. Chromosome walking
D. Gene expression
9.What is chromosome walking?
A. Hybridization technique
B. Sequencing technique
C. Genetic marker
D. Hybridization technique
10.What is the unit of a genetic map?
A. Centimeter
B. Nanometer
C. Angstrom
D. Centimeter
11.Which of the following statement is NOT true for genetic markers?
A. A gene or a DNA sequence
B. Associated with a particular trait
C. Anything can be used as a genetic marker
D. A gene or a DNA sequence
12.Which of the following is NOT a DNA marker?
A. RAPD
B. Hormone
C. RFLP
D. RAPD
13.What is the full form of RFLP?
A. Restriction Fragment Length Polymorphisms
B. Random Fragment Length Polymorphism
C. Restriction Find in Length of DNA Polymer
D. Restriction Fragment Length Polymorphisms
14.Which of the following technique is used for the amplification of DNA fragments?
A. AFLP
B. RFLP
C. RAPD
D. AFLP
15.Out of the following, which technique detect single nucleotide polymorphism?
A. RFLP
B. AFLP
C. SSLP
D. RFLP
16.Name the mapping technique used to determine the position of restriction sites in a DNA molecule?
A. Genetic map
B. Restriction mapping
C. Biochemical markers
D. Genetic map
17.What is the name of the hypervariable region of immunoglobin, which is responsible for its diversity?
A. CDR
B. Hinge region
C. Epitope
D. CDR
18.Who discovered the structure of immunoglobulin by treating it with betamercaptoethanol?
A. Nisonoff
B. Edelman
C. Porter
D. Nisonoff
19.Which of the following amino acid is found in the hinge region?
A. Alanine
B. Aspargine
C. Proline and cysteine
D. Alanine
20.Which immunoglobulin can pass through placenta?
A. IgD
B. IgE
C. IgM
D. IgD
21.Name the class of immunoglobulin which has a pentameric structure?
A. IgE
B. IgG
C. IgA
D. IgE
22.Which of these immunoglobulins is present in external secretion?
A. IgG
B. IgM
C. IgA
D. IgG
23.Name the class of immunoglobulin which takes part in hypersensitivity reaction?
A. IgG
B. IgE
C. IgA
D. IgG
24.Which of the following is responsible for B-cell activation?
A. Infection
B. Antibody
C. Antigen
D. Infection
25.What is the meaning of thymus independent B-cell activation?
A. Without the participation of T-cell
B. Do not mature in the thymus
C. Thymus would not take part in its activation
D. Without the participation of T-cell
26.Which of the following acts as a coreceptor for B-cell activation?
A. CD28
B. IL-2
C. IgA
D. CD28
27. Out of these, which transcription factor does not take part in B-cell activation?
A. Abl
B. NF- kB
C. Jun
D. Abl
28. Hybridoma technology is used to produce?
A. Interferons
B. Monoclonal antibodies
C. Antibodies
D. Interferons
29.Name the drug which is used to isolate hybridoma cells from the media?
A. Amphetamine
B. Opium
C. Aminopterin
D. Amphetamine
30.Name the most commonly used monoclonal antibody for treatment of breast cancer?
A. Bradikinins
B. Prostaglandin
C. Erbutir
D. Bradikinins
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