RNA polymerase catalyzes the synthesis of RNA by addition nucleotide monophosphate and release of pyrophosphate for nucleotide triphosphate. RNA polymerase
In prokaryotes, a holoenzyme RNA polymerase consists of four core subunits namely 2α, 1β, 1β' and a promoter recognizing σ subunit. It may also require a termination factor for termination of the
The termination of transcription occurs in both rho-dependent and rho-independent manner. Which of the following is NOT true regarding the termination of transcription
A.
rho proteins recognize C-rich region near 3'end of the newly synthesized RNA
B.
rho-independent termination occurs when the transcription reaches the palindromic structure leading to the formation of hairpins
C.
rho protein competes with RNA polymerase for binding to nucleotides
Rifamycin is an antibiotic used for the treatment of tuberculosis. It binds to .... subunit of RNA polymerase and inhibits the initiation of transcription.
