Name the class of MHC which is recognized by CD4 TH cell.
A.
MHC cannot recognize T cells
B.
MHC III
C.
MHC I
D.
MHC II
Answer: Option D
Explanation:
CD4 is a monomeric single chain which recognizes MHC II molecule and is present on T helper cell. It consists of a core extracellular domain and has three critical serine residues on a cytoplasmic tail.
Which of the following statement is INCORRECT about superantigens?
A.
Viral or bacterial proteins
B.
Endogenous by nature
C.
Unique binding ability
D.
Activate a large number of T-cells
Answer: Option B
Explanation:
Superantigens are viral or bacterial proteins which have the unique binding ability of T-cell receptor and MHC II molecules, i.e. it binds simultaneously to both and activate large numbers of T-cells. It can be both either endogenous or exogenous in nature.