Synthesis of antibodies takes place by which of the following cells?
Bone marrow cells
Answer: Option C
Antibodies are also called immunoglobulin, the antigen- binding glycoproteins, which are exclusively synthesized by B-cells and in billions of forms with different amino acid sequences and different antigen binding sites.
What is the name of the hypervariable region of immunoglobin, which is responsible for its diversity?
Answer: Option A
CDR is complementarity determining regions which impart the diversity in the variable region of both heavy and light chains. These are three small hypervariable regions and remaining part is called framework region.
Who discovered the structure of immunoglobulin by treating it with betamercaptoethanol?
Answer: Option B
Edelman discovered that when immunoglobulin treated with betamercaptoethanol, it will fall apart into four chains, i.e. two identical light chain and two large heavy chains. This result was considered to propose a structure of immunoglobulin.