Origin of replication is particular sites on DNA as replication does not start at random sites. Replication starts from a particular site and proceeds bidirectionally or unidirectionally till the terminus site.
E.coli is monorepliconic and have single replicon while eukaryotic cells contain many replication origins on a single chromosome and called multirepliconic.
Which of the following protein does not involve in the initiation of replication?
A.
DnaA
B.
SSB (Single strand binding protein)
C.
DnaB
D.
DnaF
Answer: Option D
Explanation:
In eukaryotic replication, more than 20 proteins take part out of that the initiation of replication takes place in the presence of helicase, primase, SSB, DnaC, DnaA.