Genetics - Section 2 Multiple Questions and Answers.




26.In eukaryotes, the RNA synthesis process is more complex than prokaryotes. The RNA synthesis process is regulated by chromatin structure, upstream and downstream sequences, binding partners, etc. Whic
A. Most actively transcribed genes are found in a loosely relaxed form of chromatin called euchromatin
B. The most inactive segment of DNA is found in compact chromatin structure called heterochromatin
C. Histone modification such as methylation, acetylation regulate the RNA transcription by modulating chromatin structure
D. All of the above

27.In eukaryotes, three different RNA polymerases are involved in the synthesis of a different class of RNAs namely: rRNA, tRNA, and mRNA. The RNA polymerase that is required for the synthesis of mRNA is
A. RNA polymerase I
B. RNA polymerase II
C. RNA polymerase III
D. None of the above

28.In eukaryotes, the consensus promoter sequences (TATA box) that are required for initiation of transcription is generally present
A. 10 nucleotide upstream of transcription start site (TSS)
B. 25 nucleotide upstream of TSS
C. 10 nucleotide downstream of TSS
D. 25 nucleotide downstream of TSS

29. Enhancers are special cis-acting DNA sequences that increase the rate of transcription by RNA polymerase. Which of the following is true regarding enhancers?
A. 10 nucleotide upstream elements
B. 25 nucleotide downstream elements
C. present closer or 1000s nucleotide upstream or downstream of TSS
D. All of the above

30.The capping of nucleotide prevents the rapid cleavage of mRNA and catalyzed by guanylyltransferase. Identify the nucleotide cap that is attached at the 5'end of mRNA.
A. 5-methyl guanosine
B. 7- methyl guanosine
C. 5- acetyl guanosine
D. 7- acetyl guanosine

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