Iodoacetate is an inhibitor of glyceraldehydes-3 phosphate dehydrogenase which reacts with its –SH group of cys residue and stops the glycolysis pathway.

Pyruvate oxidation takes place in the presence of oxygen inside the mitochondrial matrix and oxidized to acetyl Co-A. Pyruvate is produced in the glycolysis from where it enters to mitochondria with the help of transport protein.

The citric acid cycle is also known as Krebs cycle in which the condensation of oxaloacetate and an acetyl group of acetyl Co-A take place and produced two molecules of Co₂.

Fluoroacetate is a potent inhibitor of aconitase enzyme; it is a pesticide which blocks citric acid cycle by its metabolic conversion to fluorocitrate.

All the complexes of the electron transport chain comprise of a prosthetic group in order to act as an electron carrier. These prosthetic groups may be flavins, heme, Fe-S cluster and copper.